Results 241 to 250 of about 19,141,543 (286)

The economic burden of seasonal influenza - China, 2010-2019. [PDF]

Hum Vaccin Immunother
Chen C, He J, Chen H, Tan J, Huang X, Peng N, Zhang X, Sun Y, Liu G.   +8 more
europepmc   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Integrating Disease Burden and Cost-Effectiveness for Value-Based Prioritisation of COPD Interventions: A Narrative Review. [PDF]

Int J Chron Obstruct Pulmon Dis
Zhang R, Yang L, Jing D, Chen L.
europepmc   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Economic and epidemiological burden of HPV-related diseases in the Czech Republic: A claims database analysis. [PDF]

Hum Vaccin Immunother
Kamenský V, Alahakoon J, Zadák J, Mothejlová K, Donin G, Grand Müllerová J, Rožánek M, Tichopád A, Šarkanová I.   +8 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Economic impact of education and empowerment interventions in diabetes care: a two-year prospective longitudinal analysis in a tertiary care population. [PDF]

Front Clin Diabetes Healthc
Raghav S, Kumar S, Ashraf H, Khanna P, Raghav A.   +4 more
europepmc   +1 more source

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz, Vít Herynek, Mária Hovořáková, Zuzana Pavlíková, Linda Dalecká, Klára Steklíková, Petr Matouš, Petr Páral, Margarita Tkachenko, Filip Koucký, Fatma Nalan Cetin, Ludmila Maffei Svobodová, Jiří Beneš, Kristýna Kolouchová   +13 more
wiley   +1 more source

Health-system burden of higher-risk myelodysplastic syndromes in England: a literature-based micro-cost analysis. [PDF]

BMJ Open
Williamson J, Searle EJ, Louramo E, Hughes R, Bono P, Gc VS.   +5 more
europepmc   +1 more source

Economic burden of depressive disorders and HIV for people living with HIV in Uganda. [PDF]

Health Policy Plan
Katana PV, Ross I, Kiconco BE, Tenywa P, Neuman M, Ssembajjwe W, Sekitoleko I, Katumba KR, Kinyanda E, Laurence YV, Greco G.   +10 more
europepmc   +1 more source