Results 71 to 80 of about 22,546,014 (283)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Financial Burden of Drug-sensitive Tuberculosis in India: A Systematic Review and Meta-analysis

open access: yesPreventive Medicine: Research & Reviews
Introduction: Tuberculosis (TB) poses a significant public health and economic burden in India, with out-of-pocket expenditure (OOPE) often leading to financial distress.
Subba Krishna Nagaraj   +4 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Estimated direct medical costs per contact. Costs in Canadian dollars, 2012 valuation.

open access: yes, 2016
Estimated direct medical costs per contact. Costs in Canadian dollars, 2012 valuation.
Ipek Gurol-Urganci (2215576)   +3 more
core   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Economic Burden of Rheumatoid Arthritis in Iran: A Societal Perspective

open access: yesPublic Health Challenges
Background Rheumatoid arthritis (RA) is a progressive and chronic systemic inflammatory disease and imposes a significant economic burden on patients and societies if not controlled. This study aimed to determine the economic burden of RA in Iran in 2022.
Mehdi Rezaee   +6 more
doaj   +1 more source

Investigating the costs of major and minor cycling crashes in Tasmania, Australia

open access: yesAustralian and New Zealand Journal of Public Health, 2015
Objective: A pilot study to estimate the societal costs of cycling crashes in Tasmania. Methods: A telephone‐based questionnaire collected information on demographics, cycling habits and details of major and minor crashes.
Andrew J. Palmer   +5 more
doaj   +1 more source

Pediatric food allergy-related household costs are influenced by age, but not disease severity

open access: yesWorld Allergy Organization Journal, 2019
Objective: The economic burden of food allergy on households is poorly understood. We evaluated the household costs associated with specialist-diagnosed pediatric food allergy, with focus on age and disease severity. Study design: A cross-sectional study
Hay Mar Wai   +8 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Cost of illness of breast cancer in low- and middle-income countries: a systematic review

open access: yesHealth Economics Review
This systematic review explores the cost of illness (COI) studies on breast cancer in low- to middle-income countries (LMICs). Studies in Cochrane, Proquest Thesis, PubMed and Scopus were considered.
Siew Wei Yeong   +2 more
doaj   +1 more source

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