Results 191 to 200 of about 770,537 (308)

Direct What? - A Study of Direct Payments to Mental Health Service Users [PDF]

, 2002
Jones, Lyn, Ridley, Julie
core  

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Breast and cervical cancer care in Ghana: a qualitative exploratory study of stakeholder perspectives on National Health Insurance Scheme coverage. [PDF]

BMJ Open
Amankwah I, Gone M, Jaliu A, Morand M, Owusu R.   +4 more
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Dental Care and Oral Health Within the Framework of Bulgarian Public Health Financing. [PDF]

Healthcare (Basel)
Raycheva R, Popova-Sotirova I, Musurlieva N.   +2 more
europepmc   +1 more source

Artificial Neuron Based on Electrical Anisotropy from WSe2 Field Effect Transistors

Advanced Science, EarlyView.
An artificial neuron was realized based on the anisotropic mobility of WSe2. Dendritic and axon‐multisynaptic performance of a neuron was achieved with optical and voltage pulses. Recognition accuracy of handwritten digits was obtained to 97% based on the synaptic weight of an artificial neuron.
Qi Sun, Ping Chen, Kun Lv, Chuanwen Chen, Jinsheng Zhu, Zhiling Chen, Yaxian Lu, Ni Zhang, Zongqian Tan, Tao Lin, Caofeng Pan   +10 more
wiley   +1 more source

Time to fully account for cost in monitoring financial protection and universal health coverage in low- and middle-income settings. [PDF]

Health Policy Plan
Binyaruka P, Borghi J.
europepmc   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Equity of total health expenditure in China, 2015-2021. [PDF]

Sci Rep
Zhou M.
europepmc   +1 more source

Spectral Decomposition of Chemical Semantics for Activity Cliffs‐Aware Molecular Property Prediction

Advanced Science, EarlyView.
PrismNet mimics chemical intuition by functioning as a computational prism, refracting molecular graphs into complementary semantic views and spectral frequencies. This dual‐decomposition strategy effectively captures both global topologies and subtle “activity cliff” perturbations.
Chaoyang Xie, Junhu Xu, Guangyi Huang, Shihang Wang, Mutian He, Xinyu Dong, Huiyang Hong, Xiaojun Yao, Qi Wang, Yuquan Li   +9 more
wiley   +1 more source