Results 141 to 150 of about 1,227,025 (267)

Capturing elusive alkenyl radicals in the Wharton reaction and its interrupted cyclization. [PDF]

Chem Sci
Akkarasereenon K, Liu Y, Lai YT, Tong R.
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Dehydrative Allylic Amination in Water via a Polymer-Supported Ruthenium Catalyst. [PDF]

ChemSusChem
Mizuno S, Kubota Y, Inuzuka T, Funabiki K, Inoue M.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Piecewise Stereoselective Assembly of Multisubstituted Alkenes. [PDF]

J Am Chem Soc
Jones E, Martin RT, MacMillan DWC.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Self-Identifying Codes in Direct Products of Complete Graphs With Paths and Cycles [PDF]

Contributions to Mathematics
Jihong Liu, Hao Qi, Zhangwei Shan
doaj   +1 more source

Lucigenin: a strongly oxidizing dicationic photocatalyst for the direct azolation of arenes. [PDF]

Chem Sci
Matei A, Roure B, Chen X, Beil SB, Feringa BL.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Iron-Catalyzed Oxidative Coupling under Aerobic Conditions: A Decade of Progress. [PDF]

ACS Omega
D C C, Prabhu N, Kulkarni SD, Shetty NS.
europepmc   +1 more source