Results 141 to 150 of about 1,304,856 (308)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Semi-Direct Product of Edge Colored Graphs
, 2005 A distance can be defined on a complete graph, called an edge colored graph. Edge colored graphs have many properties; however, this paper is mostly concerned with homogeneity and algebraic properties of edge colored graphs.
O\u27Connor, Charles
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Characterizing Direct Product Testing via Coboundary Expansion
STOC ’24, June 24–28, 2024, Vancouver, BC, CanadaA d-dimensional simplicial complex X is said to support a direct product tester if any locally consistent function defined on its k-faces (where k≪ d) necessarily come from a function over its vertices ...
Bafna, Mitali, Minzer, Dor
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Foreign Direct Investment and the Operations of Multinational Firms: Concepts, History, and Data [PDF]
The concept and measurement of foreign direct investment have changed over time, and what is measured by balance of payments flows and stocks is quite different from what is implied by theories of direct investment.
Robert E. Lipsey
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Produk Langsung Lengkap dari Grup
Journal of Mathematical and Fundamental Sciences, 2019 Let Γ = {Gi} be a countable collection of groups. Then its cartesian product can be made into a group in a very obvious way. This new group is called the external direct product of the groups Gi from the collection Γ.
K. Kromodihardjo
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
INTERNATIONAL TRADE AND FOREIGN DIRECT INVESTMENT: SUBSTITUTES OR COMPLEMENTS?
International agricultural trade has evolved over time. Processed foods and developing countries have become major growth markets for U.S. agricultural exports, and foreign direct investment (FDI) has become even more important than exports as a means of
Marchant, Mary A. +2 more
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