Results 71 to 80 of about 1,304,856 (308)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

APLIKASI GENERATOR AKORD DENGAN MENGGUNAKAN FONT NOTANGKA.TTF DAN MENGADAPTASI LOGIKA DIRECT PRODUCT PADA NOTASI MUSIKAL ANGKA

open access: yesJurnal Informatika, 2009
Information technology has brought a big influence in other fields of science, especially in music. One part of the musical arrangement process is chord defining. Direct product is one of vector multiplication types.
Eko Sediyono   +2 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Direct product B1 near-ring [PDF]

open access: yes, 2018
Dalam tesis ini dibahas tentang direct product dari B1 near-ring.
Fikrianti, Dian
core  

On Generalized Direct Product of Fuzzy Multigroups

open access: yes, 2020
<p>Fuzzy multigroup is a structure that generalizes the idea of fuzzy group. In fact, the concept of fuzzy multigroups is the application of fuzzy multisets to group theory. The idea of direct product of fuzzy multigroups has been established. This
P.A. Ejegwa
core   +1 more source

On Atanassov's intuitionistic fuzzy grade of the direct product of two hypergroupoids

open access: yesKuwait Journal of Science, 2014
In this paper we continue the study of the sequences of join spaces and Atanassov's intuitionistic fuzzy sets associated with the direct product of two hypergroupoids with special properties and we determine the Atanassov's intuitionistic fuzzy grade of ...
BIJAN DAVVAZ, E. HASSANI SADRABADI
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Globalization Drives Strategic Product Switching. [PDF]

open access: yes
Using firm-level data for Estonia for the years 1997-2005, we analyze the impact of international competition on firm dynamics, considering both firm closedown and product switching.
Slootmaekers, Veerle   +2 more
core  

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