Results 101 to 110 of about 891,818 (308)

The direct access search system

open access: yesProceedings of the November 12-14, 1963, fall joint computer conference on XX - AFIPS '63 (Fall), 1963
The development of mechanized information retrieval systems has been rapid. Successful operating systems have been established and new ones are being set up almost every day. Techniques not practical with manual systems have been developed, notably in the searching of deep indexes.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Visual search and VDUS [PDF]

open access: yes, 1991
This wide-ranging study explored various parameters of visual search in relation to computer screen displays. Its ultimate goal was to help identify factors which could result in improvements in commercially available displays within the 'real world ...
Scott, Derek, Scott, D
core  

Optimal Design of Round Bottomed Triangle Channels

open access: yesTikrit Journal of Engineering Sciences, 2010
In optimal design concept, the geometric dimensions of a channel cross-section are determined in a manner to minimize the total construction costs. The Direct search optimization method by using MATALAB is used to solve the resulting channel optimization
Ayman T. Hameed
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Worst case complexity of direct search [PDF]

open access: yes, 2010
In this paper we prove that direct search of directional type shares the worst case complexity bound of steepest descent when sufficient decrease is imposed using a quadratic function of the step size parameter.
Vicente, L. N.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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