Results 161 to 170 of about 891,818 (308)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Incorporating minimum Frobenius norm models in direct search
, 2008 The goal of this paper is to show that the use of minimum Frobenius norm quadratic models can improve the performance of direct-search methods. The approach taken here is to maintain the structure of directional direct-search methods, organized around a ...
H. Rocha +5 more
core
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Direct search algorithm for bilevel programming problems
Bilevel programming, Nonsmooth optimization, Solution algorithm, Direct search algorithm, Clarke stationary solution,
Ayalew Mersha, Stephan Dempe
core +1 more source
Direct enrolment and direct update: the Australian experience [PDF]
, 2012 Australia has required all eligible electors to enrol (register) to vote now for one hundred years. In recent years, however, changing demographic patterns and citizen mobility have made it increasingly challenging to maintain the accuracy and currency ...
core
Running-in Position Determination of Centralizer for Anti-eccentric Wearing of Directional Well
Shiyou jixie, 2016 In the design of centralizer,it is usually assumed that the sucker rod coupling and the centralizer to be straight bars with equivalent cross-sectional areas.This is a bias that should be corrected.Based on the feature that sucker rod string with ...
Fu Yarong
doaj
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Exploring the relationship between direct and indirect spillovers from FDI in Argentina
This paper seeks to examine the paradox that despite the growing role of FDI in most economies and growth in their share of employment, exports and innovation (‘direct spillovers’), evidence of technological spillovers to domestic firms in the host ...
Marin ,Anabel, Narula ,Rajneesh
core
SEARCHING FOR HUMAN CAPITAL DETERMINANTS OF FOREIGN DIRECT INVESTMENT INFLOWS IN THE EU NEW MEMBER STATES [PDF]
The specific levels and patterns of foreign direct investment in the Central and EasternEuropean countries could not be fully explained taking into account only the traditional economicdeterminants, as shown in the empirical studies undertaken so far ...
Ioan Talpos, Cosmin Enache
core