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Sequence Directed Hybrid Fuzzing
2020 IEEE 27th International Conference on Software Analysis, Evolution and Reengineering (SANER), 2020Existing directed grey-box fuzzers are effective compared with coverage-based fuzzers. However, they fail to achieve a balance between effectiveness and efficiency, and it is difficult to cover complex paths due to random mutation. To mitigate the issue, we propose a novel approach, sequence directed hybrid fuzzing (SDHF), which leverages a sequence ...
Hongliang Liang +3 more
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Direct Sequencing of PCR Products
2003Sequencing is an increasingly important part of the analysis of a polymerase chain reaction (PCR) product and is used in many areas of hemostasis. The protocols described in this chapter have been used to sequence many different PCR templates and provide high-quality, reproducible sequence data.
J C, Harwood, G A, Phear
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Direct Sequencing of PCR-Amplified DNA
Molecular Biotechnology, 1994This article describes the direct sequencing of PCR-amplified DNA, a technique that bypasses the problem of replication errors sometimes associated with other PCR procedures. The direct sequencing procedure produces an "average sequence" of all the copies of the target. Any miscopied molecule usually represents only a small proportion of the total. The
P M, Green, F, Giannelli
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Sequence-Directed Curvature Of Dna
Annual Review of Biochemistry, 1986DNAs from both prokaryotic and eukaryotic organisms have yielded restriction fragments which manifest markedly anomalous electrophoretic behaviour (reduced mobility) when run on polyacrylamide gels. We have shown previously that the abnormal electrophoretic behaviour of one such fragment is a consequence of stable curvature of the helix axis in ...
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2003
Advances in DNA sequencing techniques have made it possible to routinely sequence long DNA molecules (1,2). Recently double-stranded DNA has been directly sequenced with chain terminators (3), and this eliminates the tedious task of subcloning the fragments into single-stranded M13 vectors.
A, Graham, J, Steven, D, McKechnie
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Advances in DNA sequencing techniques have made it possible to routinely sequence long DNA molecules (1,2). Recently double-stranded DNA has been directly sequenced with chain terminators (3), and this eliminates the tedious task of subcloning the fragments into single-stranded M13 vectors.
A, Graham, J, Steven, D, McKechnie
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Direction and Sequence in Copying
Journal of Cross-Cultural Psychology, 1973To explore the nature of directional experience and directional behavior in countries with different scripts, children and adults in the United States and in Israel were asked to copy a number of geometric shapes. The paths or sequences of strokes displayed some common developmental trends together with some specific differences stemming from the ...
Jacqueline Goodnow +3 more
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Performance of direct-sequence systems with long pseudonoise sequences
IEEE Journal on Selected Areas in Communications, 1992A performance analysis of direct-sequence systems with long pseudonoise sequences is presented. The assessment of the symbol error probability in the presence of multiple-access interference is stressed, but other types of interference are also considered for completeness. Both binary and quaternary spreading waveforms are treated.
exaly +2 more sources
Specific-primer-directed DNA sequencing
Analytical Biochemistry, 1986A simple and rapid strategy for DNA sequence analysis based on the Sanger chain-termination method is described. This procedure utilizes full-sized inserts of 1 to 4 kb of DNA cloned into M13 bacteriophage vectors. After the sequence of the first 600-650 bp of the insert DNA has been determined with the commercially available universal vector primer, a
E C, Strauss +3 more
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