Results 51 to 60 of about 5,999,057 (304)

Word order in utterances of direct speech in English: a subtle balance between conventions and innovation

open access: yesE-REA, 2013
Word order in an utterance produced by a speaker in connected speech is not supposed to be chaotic. Even though word order differs from one language to another, a given person who speaks his/her own mother tongue is normally able to say whether a given ...
Grégoire LACAZE
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Whole Genome Sequencing of Hepatitis A Virus Using a PCR-Free Single-Molecule Nanopore Sequencing Approach

open access: yesFrontiers in Microbiology, 2020
Hepatitis A virus (HAV) is one of the most common causes of acute viral hepatitis in humans. Although HAV has a relatively small genome, there are several factors limiting whole genome sequencing such as PCR amplification artefacts and ambiguities in de ...
Frederico M. Batista   +9 more
doaj   +1 more source

Generalizable Direct Protein Sequencing With InstaNexus

open access: yesMolecular & Cellular Proteomics
Accurate determination of protein sequences is central to biology. Protein-based therapeutics, such as antibodies and nanobodies, are not encoded in reference genomes, challenging their accurate characterization via standard proteomics. Current methods rely on indirect inference, fragmented outputs, and labor-intensive workflows, which hinder ...
Marco Reverenna   +14 more
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

PN Sequence Period Estimation Method for Underwater Direct-Sequence Spread Spectrum Signals Under Low SNR

open access: yesJournal of Marine Science and Engineering
In non-cooperative DSSS signal reception, the accurate estimation of the pseudo-noise (PN) sequence period is essential for successful despreading and information recovery.
Yuanxin Teng   +6 more
doaj   +1 more source

Modeling Directional Monotonicity in Sequence with Copulas

open access: yesAxioms
In this paper, we present the concept of being monotonic in sequence according to a specific direction for a collection of random variables. This concept broadens the existing notions of multivariate dependence, such as sequential left-tail and right-tail dependence.
José Juan Quesada-Molina   +1 more
openaire   +4 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A CHEAP ZILOG MP APPLIED TO SPREAD SPECTRUM SYSTEMS DESIGN

open access: yesJournal of Engineering and Sustainable Development, 2018
The Z2000 Evaluation Board performing direct sequence spread spectrum processing, a 900 MHz radio receiver, and a transmitter module was applied to build a Direct sequence spread spectrum transceiver, RF board was designed & implemented for the purpose ...
Rajaa aldeen Abad Khalid
doaj  

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