Results 91 to 100 of about 4,150,724 (291)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Bounded Approximate Decentralised Coordination via the Max-Sum Algorithm [PDF]

open access: yes, 2011
In this paper we propose a novel approach to decentralised coordination, that is able to efficiently compute solutions with a guaranteed approximation ratio. Our approach is based on a factor graph representation of the constraint network.
Farinelli, A.   +14 more
core   +1 more source

Relative injectivity and CS-modules

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1994
In this paper we show that a direct decomposition of modules M⊕N, with N homologically independent to the injective hull of M, is a CS-module if and only if N is injective relative to M and both of M and N are CS-modules. As an application, we prove that
Mahmoud Ahmed Kamal
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Weighted Sum of Correlated Lognormals: Convolution Integral Solution [PDF]

open access: yes, 2011
Probability density function (pdf) for sum of n correlated lognormal variables is deducted as a special convolution integral. Pdf for weighted sums (where weights can be any real numbers) is also presented.
Nagy, Tamás
core   +1 more source

Summing up and future directions

open access: yes, 1996
Abstract This chapter reviews the main points of the book, emphasizing the definition of migration based on physiological interactions including inhibition, the evolution of migration syndromes, and the relation between migration and ephemeral and patchy habitats in both space and time. It stresses the need to examine migration across
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

WTO direct action convergence, Seattle, WA (nov. 20-28), registration application [verso]

open access: yes, 1999
Alternate title: DAN registration. Affiliated web page url: www.agitprop.org/artandrevolution/wto. Also sent out as document 6 of 19 in a Direct Action Network (DAN) organizing packet; these documents are contained in a 9 X 12 inch envelope stating ...
Direct Action Network (DAN)
core  

On totally projective QTAG-modules

open access: yesJournal of Taibah University for Science, 2019
A module M over an associative ring R with unity is a QTAG-module if every finitely generated submodule of any homomorphic image of M is a direct sum of uniserial modules.
Fahad Sikander, Tanveer Fatima
doaj   +1 more source

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