Results 81 to 90 of about 638,457 (261)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On totally projective QTAG-modules
Journal of Taibah University for Science, 2019 A module M over an associative ring R with unity is a QTAG-module if every finitely generated submodule of any homomorphic image of M is a direct sum of uniserial modules.
Fahad Sikander, Tanveer Fatima
doaj +1 more source
Journal of Mathematical Analysis and Applications, 2014 Abstract This paper investigates when a bounded operator on Hilbert space has the property that its square is similar to to the direct sum of it with itself. A few general results are obtained and the normal operators and unilateral shifts having this property are characterized. Several additional examples are explored.
John B. Conway +2 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Semi-Simple Extension of the (Super) Poincaré Algebra
Advances in High Energy Physics, 2009 A semi-simple tensor extension of the Poincaré algebra is proposed for the arbitrary dimensions D. It is established that this extension is a direct sum of the D-dimensional Lorentz algebra so(D−1, 1) and D-dimensional anti-de Sitter (AdS) algebra so(D−1,
Dmitrij V. Soroka, Vyacheslav A. Soroka
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Estimating the First, Hyper-Zagreb Index for Direct Product of F-Sum Graphs
MathematicsA chemical graph is an illustration of a chemical compound’s structural formula, where the edges indicate covalent bonding and the vertices depict atoms.
Suha Wazzan, Rauf Irshad
doaj +1 more source
On the spectra of non-selfadjoint differential operators and their adjoints in direct sum spaces
International Journal of Mathematics and Mathematical Sciences, 2003 The general ordinary quasidifferential expression Mp of nth order, with complex coefficients and its formal adjoint Mp+ on any finite number of intervals Ip=(ap,bp), p=1,…, N, are considered in the setting of the direct sums of Lwp2(ap ...
Sobhy El-Sayed Ibrahim
doaj +1 more source