Results 241 to 250 of about 656,194 (294)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Genetic architecture of swine inflammation and necrosis syndrome and its genetic correlation with repeated skin damage scores. [PDF]

J Anim Sci
Oliveira Garcia A, Galoro Leite N, Vogelzang R, Bretanha Rocha RF, Facioni Guimarães SE, Lourenco D.   +5 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Understanding the effect of educational attainment on the risk of retinal detachment: a Mendelian randomization mediation analysis. [PDF]

Int J Retina Vitreous
Katsimpris A, Baumeister SE, Baurecht H, Blaikie A, Goudie C, Tatham AJ, Nolde M.   +6 more
europepmc   +1 more source

When air-raid sirens howl the rate of visits of pregnant women to the obstetrical emergency room decreases: results of a 4-months wartime follow up in a tertiary medical center. [PDF]

BMC Pregnancy Childbirth
Shaham L, Blumenfeld S, Brenner N, Segal G, Simchen M, Cahan T, Zloto K, Sivan E, Weissmann-Brenner A.   +8 more
europepmc   +1 more source

Neural sequences underlying directed turning in Caenorhabditis elegans. [PDF]

Nat Neurosci
Kramer TS, Wan FK, Pugliese SM, Atanas AA, Pradhan S, Hiser AW, Godinez LM, Luo J, Bueno E, Felt T, Flavell SW.   +10 more
europepmc   +1 more source

Toward universal dose prediction: A multi-scale, multi-objective framework for sequential boost radiotherapy. [PDF]

Med Phys
Maniscalco AM, Zhong X, Domal S, Lin YC, Sher D, Lin MH, Jiang S, Nguyen D.   +7 more
europepmc   +1 more source

Linguistic and psychometric validation of a German version of the measure of moral distress for healthcare professionals (MMD-HP GER): results of a study with intensive care nurses. [PDF]

BMC Med Ethics
Forster L, Byrne S, Spielmann-Burkard H, Weber S, von Strachwitz M, Kuehlmeyer K, Kugler C.   +6 more
europepmc   +1 more source

Sitting and Active Meditation Practice: Utilization and Associations with Outcomes in Naturalistic and Clinical Trial Data. [PDF]

Mindfulness (N Y)
Goldberg SB, Jiwani Z, Dahl CJ, Tatar R, Dunne JD, Davidson RJ, Hirshberg MJ.   +6 more
europepmc   +1 more source