Results 71 to 80 of about 643,665 (260)
Coerciveness and isomorphism of discontinuous Sturm-Liouville problems with transmission conditions
This study investigates a discontinuous Sturm-Liouville boundary value problem(BVP) on two intervals with functionals and transmission conditions in the direct sum ofSobolev spaces. Moreover, it presents the differential operator generated by the problem
Murat Küçük, Mustafa Kandemir
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Spectrum of the direct sum of operators
We study the connection between spectral properties of direct the sum of operators in the direct sum of Hilbert spaces and its coordinate operators.
Elif Otkun Cevik, Zameddin I. Ismailov
doaj
On decomposable pseudofree groups
An Abelian group is pseudofree of rank ℓ if it belongs to the extended genus of ℤℓ, i.e., its localization at every prime p is isomorphic to ℤpℓ.
Dirk Scevenels
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Systematics of U-spin sum rules for systems with direct sums
A rich mathematical structure underlying flavor sum rules has been discovered recently. In this work, we extend these findings to systems with a direct sum of representations. We prove several results for the general case.
Margarita Gavrilova, Stefan Schacht
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An abstract approach to some spectral problems of direct sum differential operators
In this paper, we study the common spectral properties of abstract self-adjoint direct sum operators, considered in a direct sum Hilbert space. Applications of such operators arise in the modelling of processes of multi-particle quantum mechanics ...
Maksim S. Sokolov
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

