Results 71 to 80 of about 643,665 (260)

Coerciveness and isomorphism of discontinuous Sturm-Liouville problems with transmission conditions

open access: yesJournal of New Results in Science
This study investigates a discontinuous Sturm-Liouville boundary value problem(BVP) on two intervals with functionals and transmission conditions in the direct sum ofSobolev spaces. Moreover, it presents the differential operator generated by the problem
Murat Küçük, Mustafa Kandemir
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Spectrum of the direct sum of operators

open access: yesElectronic Journal of Differential Equations, 2012
We study the connection between spectral properties of direct the sum of operators in the direct sum of Hilbert spaces and its coordinate operators.
Elif Otkun Cevik, Zameddin I. Ismailov
doaj  

On decomposable pseudofree groups

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1999
An Abelian group is pseudofree of rank ℓ if it belongs to the extended genus of ℤℓ, i.e., its localization at every prime p is isomorphic to ℤpℓ.
Dirk Scevenels
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Systematics of U-spin sum rules for systems with direct sums

open access: yesJournal of High Energy Physics
A rich mathematical structure underlying flavor sum rules has been discovered recently. In this work, we extend these findings to systems with a direct sum of representations. We prove several results for the general case.
Margarita Gavrilova, Stefan Schacht
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An abstract approach to some spectral problems of direct sum differential operators

open access: yesElectronic Journal of Differential Equations, 2003
In this paper, we study the common spectral properties of abstract self-adjoint direct sum operators, considered in a direct sum Hilbert space. Applications of such operators arise in the modelling of processes of multi-particle quantum mechanics ...
Maksim S. Sokolov
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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