Results 121 to 130 of about 43,448 (306)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Form of filters of semisimple modules and direct sums

open access: yes, 2013
Some collections of submodules of a module defined by certain conditions are studied. A generalization of the notion of radical (preradical) filter is considered.
Maturin, Yu.
core   +1 more source

Primary decomposition of torsion R[X]-modules

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1994
This paper is concerned with studying hereditary properties of primary decompositions of torsion R[X]-modules M which are torsion free as R-modules. Specifically, if an R[X]-submodule of M is pure as an R-submodule, then the primary decomposition of M ...
William A. Adkins
doaj   +1 more source

Summing up and future directions

open access: yes, 1996
Abstract This chapter reviews the main points of the book, emphasizing the definition of migration based on physiological interactions including inhibition, the evolution of migration syndromes, and the relation between migration and ephemeral and patchy habitats in both space and time. It stresses the need to examine migration across
openaire   +1 more source

A comprehensive and robust procedure for obtaining the nofit polygon using Minkowski sums

open access: yes, 2005
The nofit polygon is a powerful and effective tool for handling the geometric requirements of solution approaches to irregular cutting and packing problems. Although the concept was first described in 1966, it was not until the early 90s that the general
Song, Xiang, Bennell, Julia A.
core  

Decomposition of a matrix as sums of direct products. Applications to neural networks

open access: yes, 1969
The rank of a matrix can be expressed as the least number of sums of direct products into which the matrix can be decomposed.
DE LUCA, ALDO, RICCIARDI, LUIGI MARIA
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A note on geometrical properties of Banach spaces using ψ-direct sums

open access: yes, 2007
Let X be a Banach space and ψ a continuous convex function on [0,1] satisfying certain conditions. Let X⊕ψX be the ψ-direct sum of X. In this note, we characterize the strict convexity, uniform convexity and uniformly non-squareness of Banach spaces ...
Saito, Kichi-Suke, Mitani, Ken-Ichi
core   +1 more source

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