Results 171 to 180 of about 250,904 (303)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Optimal Trajectory Planning of a Cable-Driven Parallel Robot by Direct Collocation Approaches

open access: yesInternational Journal of Advanced Design and Manufacturing Technology
Trajectory planning in cable-driven robots is more challenging than rigid-link ones. To maintain the robot control, the cable tensions must be positive during motion.
Milad Badrikouhi, Mahdi Bamdad
doaj  

Early repair of proximal sciatic nerve transection following skiing accidents. [PDF]

open access: yesBrain Spine
Birkeland P   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Foreign Direct Investment in Latin America and the Caribbean, 2025. Executive summary

open access: yes
The Economic Commission for Latin America and the Caribbean (ECLAC) presents the 2025 version of its annual report Foreign Direct Investment in Latin America and the Caribbean amid global uncertainty and high geopolitical tension, which are worsening the

core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Sheath Rupture in Figure-Of-Eight Suturing: A Case Report and Risk Reduction Strategies. [PDF]

open access: yesClin Case Rep
Kobayashi T   +7 more
europepmc   +1 more source

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