Results 71 to 80 of about 143 (103)

Biodegradable Iodinated Polymeric Nanoparticle as a Computed Tomography Contrast Agent for Direct Imaging of Cerebral Thrombus

ACS Nano
Hyun Jae Park, Subin Park, In Jae Chung, Hee Jeong Jang, Leesu Lee, Tae Hoon Kim, Dong-Eog Kim, Cheol-Hee Ahn   +7 more
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Magnetic resonance direct thrombus imaging: a novel technique for imaging venous thromboemboli

Thrombosis and Haemostasis, 2003
SummaryInvasive testing is now seldom required in patients with suspected venous thromboembolism (VTE). However, a corollary of noninvasive imaging is increased complexity as results are often yielded as probabilities rather than definitive answers and additional testing is frequently required following initial imaging.
James, Kelly, Beverley J, Hunt, Alan, Moody   +2 more
exaly   +3 more sources

Direct magnetic resonance imaging of carotid artery thrombus in acute stroke

Lancet, The, 1999
Stroke remains a common cause of morbidity and mortality and affects over 100 000 people per year in the UK. Thromboembolism complicating atheromatous disease within the carotid arteries is the major predisposing cause. Management of patients will be assisted if strokes that arise in this way can be distinguished reliably from those caused by emboli of
John Gladman, G Lennox
exaly   +3 more sources

Diagnosis of Lower-Limb Deep Venous Thrombosis: A Prospective Blinded Study of Magnetic Resonance Direct Thrombus Imaging

Annals of Internal Medicine, 2002
Current magnetic resonance techniques generate high signal from venous blood and show thrombi as filling defects. Magnetic resonance direct thrombus imaging (MRDTI) directly visualizes acute thrombus.To determine the accuracy of MRDTI for diagnosis of acute symptomatic deep venous thrombosis (DVT) below and above the knee.Prospective, blinded study.A ...
Alan Moody, Paul Morgan, Anne L Martel
exaly   +3 more sources

Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents

Nuclear Medicine and Biology, 2003
Two DNA aptamers directed against two separate exosites on human alpha-thrombin were evaluated for thrombus-imaging potential. Aptamer ODN 1 is directed to the thrombin substrate binding site (exosite 1). Our finding that ODN 1 competes with fibrin for binding to exosite 1 on thrombin suggests that ODN 1 will not be useful for thrombus imaging. Aptamer
Hayes, Dougan, Jeffrey I, Weitz, Alan R, Stafford, Kris D, Gillespie, Petr, Klement, John B, Hobbs, Donald M, Lyster   +6 more
openaire   +2 more sources

Hyperacute direct thrombus imaging using computed tomography and gold nanoparticles

Annals of Neurology, 2013
ObjectiveAdvancing the understanding and management of thromboembolic stroke requires simple and robust new methods that would be useful for the in vivo assessment of thrombus burden/distribution and for characterizing its evolution in a prompt and quantitative manner.MethodsAnimals (n=127) with experimental models of thrombosis were imaged with ...
Dong-Eog, Kim, Jeong-Yeon, Kim, In-Cheol, Sun, Dawid, Schellingerhout, Su-Kyoung, Lee, Cheol-Hee, Ahn, Ick Chan, Kwon, Kwangmeyung, Kim   +7 more
openaire   +2 more sources

USPIO-enhanced Direct MR Imaging of Thrombus: Preclinical Evaluation in Rabbits

Radiology, 2001
To test the hypothesis that ultrasmall superparamagnetic iron oxide (USPIO) particles may diffuse into nonendothelialized fresh thrombi and thus allow for direct magnetic resonance (MR) imaging of a thrombus.Stagnation thrombi of different thrombus ages (1, 3, 5, 7, and 9 days) were induced in the external jugular veins of 25 rabbits. Direct MR imaging
S A, Schmitz, S, Winterhalter, S, Schiffler, R, Gust, S, Wagner, M, Kresse, S E, Coupland, W, Semmler, K J, Wolf   +8 more
openaire   +2 more sources

Lower-limb deep venous thrombosis: direct MR imaging of the thrombus.

Radiology, 1998
To determine the feasibility of diagnosing deep venous thrombosis (DVT) with direct three-dimensional magnetic resonance (MR) imaging of the thrombus.Eighteen patients with proved DVT at conventional venography were evaluated with a magnetization-prepared three-dimensional blood- and fat-suppressed MR imaging sequence.
A R, Moody, J G, Pollock, A R, O'Connor, M, Bagnall   +3 more
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Magnetic resonance direct thrombus imaging differentiates acute recurrent ipsilateral deep vein thrombosis from residual thrombosis

Blood, 2014
Key Points Diagnostic management of ipsilateral recurrent DVT of the leg is complicated because residual DVT is common and mimics acute DVT on CUS. MRDTI is able to reproducibly distinguish acute ipsilateral recurrent DVT from 6-month-old chronic residual thrombi in the leg veins.
Tan, M., Mol, G.C., Rooden, C.J. van, Klok, F.A., Westerbeek, R.E., Sol, A.I. del, Ree, M.A. van de, Roos, A. de, Huisman, M.V.   +8 more
openaire   +4 more sources

Is Deep-Vein Thrombosis Always the Origin of Pulmonary Embolism? Imaging of Veins with a Total-Body Direct Thrombus MRI Technique

Blood, 2011
Abstract Abstract 2297 Introduction Pulmonary embolism (PE) is thought to originate from embolisation of a deep-vein thrombosis (DVT), resulting in two clinical manifestations of one disease: venous thrombosis.
Langevelde, K. van, Sramek, A., Vincken, P.W.J., Rooden, J.K. van, Rosendaal, F.R., Cannegieter, S.C.   +5 more
openaire   +2 more sources