Results 91 to 100 of about 5,706,250 (297)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
مجلة الآدابEve Ensler’s play Necessary Targets (1996) dramatises how violence in Bosnia must be understood within the context of epistemic violence exercised by the ideological apparatuses of the western powers.
Ghadeer Abbas, Alyaa Naser
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Intergenerational Transmission of Violence from the Family-of-Origin to the Current Family
نشریه پرستاری ایران, 2018 Background & Aims: Domestic violence is an annoying and undeniable fact in today’s world. This study aimed to investigate the intergenerational transmission of violence from the family-of-origin to the current family in women who referred to the court ...
S Azadi, F Nahidpoor
doaj
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Sociology of gender violence in Spain. A proposed analysis
Revista de Paz y Conflictos, 2015 Johan Galtung coined the concept of «triangle of violence» to explain the dynamics of the generation of violence in social conflicts. According to this author, violence is like an iceberg in which the visible violence (or direct violence) is only a part ...
Mercedes Alcañiz
doaj
Risk of Suicide among Women Survived Domestic Violence in Erbil Governorate
Erbil Journal of Nursing and Midwifery, 2019 Background and objectives: Domestic violence is a global issue leading to many medical and mental health consequences. A stable family relationship is mandatory for physical and mental health.
Diana Aprem Kako +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source