Results 91 to 100 of about 76,358 (278)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Fast estimation of array shape and direction of arrival using sparse Bayesian learning for manoeuvring towed line array

IET Radar, Sonar & Navigation
The sparse Bayesian learning (SBL) algorithm has demonstrated its advantage in the direction of arrival (DOA) estimation. However, it requires a lot of computational cost to iteratively estimate the SBL hyperparameters from measurement data.
Xiang Pan, Haoran Wang, Min Li, Jie Zhou, Yuxiao Li, Weize Xu   +5 more
doaj   +1 more source

Approximate maximum likelihood direction of arrival estimation for two closely spaced sources [PDF]

, 2013
—Most high resolution direction of arrival (DoA) estimation algorithms exploit an eigen decomposition of the sample covariance matrix (SCM). However, their performance dramatically degrade in case of correlated sources or low number of snapshots.
Besson, Olivier, Chaumette, Eric, Vincent, François   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Root-MUSIC-based joint TOA and DOA estimation in IR-UWB

Tongxin xuebao, 2014
The parameters can be estimated via two-dimensional (2D) multiple signal classification (MUSIC) algorithm, in which the two-dimensional spectral peak searching, however, requires much higher computational complexity.
Fang-qiu WANG, Xiao-fei ZHANG, Fei WANG
doaj   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Underground positioning method of single base station DOA and TOA based on single reflectio

Gong-kuang zidonghua, 2015
In view of problem of big error in underground single base station positioning system due to wireless signal influenced by multipath effect and non-line of sight, a joint estimation positioning method of DOA and TOA based on single reflection was ...
HUANG Kai, ZHAI Yanrong, ZHANG Pengcheng, ZHU Mengying   +3 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Adaptive channel selection for DOA estimation in MIMO radar

, 2017
We present adaptive strategies for antenna selection for Direction of Arrival (DoA) estimation of a far-field source using TDM MIMO radar with linear arrays. Our treatment is formulated within a general adaptive sensing framework that uses one-step ahead
Brüggenwirth, Stefan, González-Huici, María A., Mateos-Núñez, David, Simoni, Renato   +3 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source