Results 91 to 100 of about 124,553,511 (357)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Acoustic multi target tracking using direction-of-arrival batches [PDF]

open access: yes
In this paper, we propose a particle filter acoustic direction-of-arrival (DOA) tracker to track multiple maneuvering targets using a state space approach. The particle filter determines its state vector using a batch of DOA estimates.
Velmurugan, Rajbabu   +2 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Fast estimation of array shape and direction of arrival using sparse Bayesian learning for manoeuvring towed line array

open access: yesIET Radar, Sonar & Navigation
The sparse Bayesian learning (SBL) algorithm has demonstrated its advantage in the direction of arrival (DOA) estimation. However, it requires a lot of computational cost to iteratively estimate the SBL hyperparameters from measurement data.
Xiang Pan   +5 more
doaj   +1 more source

Comparative study for broadband direction of arrival estimation techniques

open access: yes, 2012
This paper reviews and compares three different linear algebraic signal subspace techniques for broadband direction of arrival estimation --- (i) the coherent signal subspace approach, (ii) eigenanalysis of the parameterised spatial correlation matrix ...
Weiss, Stephan   +3 more
core  

High-Precision Fast Direction-of-Arrival Estimation Method for Planar Array

open access: yes, 2023
The multiple signal classification method for direction-of-arrival estimation is widely applied in practical scenarios. However, the multiple signal classification method with planar array requires 2-dimensional on-grid spectrum searches, which would ...
Shuai Li   +6 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Root-MUSIC-based joint TOA and DOA estimation in IR-UWB

open access: yesTongxin xuebao, 2014
The parameters can be estimated via two-dimensional (2D) multiple signal classification (MUSIC) algorithm, in which the two-dimensional spectral peak searching, however, requires much higher computational complexity.
Fang-qiu WANG, Xiao-fei ZHANG, Fei WANG
doaj   +2 more sources

Study of water Cherenkov detector designs to determine air shower arrival direction with accuracy [PDF]

open access: gold, 2023
A. Shiomi   +8 more
openalex   +1 more source

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