Results 121 to 130 of about 77,971 (296)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Analysis and Simulation of Frost's Beamformer [PDF]

, 2003
Sensor arrays are often used for a signal separation from noises using the information about the direction of arrival. The aim of this paper is to analyze Frost's beamformer with respect to the speech preprocessing for the hearing impaired people.
Sovka, Pavel, Strupl, Miroslav
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Bayesian CRLB for hybrid ToA and DoA based wireless localization with anchor uncertainty [PDF]

, 2015
In this paper, we derive the Bayesian Cramér-Rao lower bound for three dimensional hybrid localization using time-of-arrival (ToA) and direction-of-arrival (DoA) types of measurements.
Abreu, Guiseppe, Steendam, Heidi, Van de Velde, Samuel   +2 more
core  

Direction of Arrival Estimation With Low Resolution Quantised Data: A Taxonomy and Survey

IET Radar, Sonar & Navigation
This paper presents a comprehensive survey of Direction of Arrival (DoA) estimation techniques that utilise one‐bit and low‐resolution data. We delve into various approaches, including direct application of quantised data to existing DoA estimators and ...
Yasin Azhdari, Mahmoud Farhang
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Robust DOA estimation for two‐level nested arrays in unknown mutual coupling

Electronics Letters
Aiming at solving the problem that the capability of direction of arrival method for estimation of nested arrays decreases sharply under unknown mutual coupling, an iterative weighted low‐rank matrix reconstruction algorithm is proposed here.
Shun He, Xue Li, Bing Sun
doaj   +1 more source

Optimizing Planar Antenna Arrays Using Genetic Algorithms for Enhanced Radar Performance in Direction of Arrival Estimation

Journal of Engineering and Sustainable Development
This paper proposes the optimization of planar antenna arrays for DOA estimation enhancement in radar systems, where accuracy and computational efficiency need to be well balanced.
Methq Kadhum Alnoori, Malik Jasim Farhan, Enas F. Rawashdeh   +2 more
doaj   +1 more source