Results 81 to 90 of about 716,657 (292)
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Due to the action of the intervening cosmic magnetic fields, ultra-high energy cosmic rays (UHECRs) can be deflected in such a way as to create clustered energy-ordered filamentary structures in the arrival direction of these particles, the so-called ...
Batista, R. Alves, Kemp, E., Zimbres, M.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Root-MUSIC-based joint TOA and DOA estimation in IR-UWB
The parameters can be estimated via two-dimensional (2D) multiple signal classification (MUSIC) algorithm, in which the two-dimensional spectral peak searching, however, requires much higher computational complexity.
Fang-qiu WANG, Xiao-fei ZHANG, Fei WANG
doaj +2 more sources
The sparse Bayesian learning (SBL) algorithm has demonstrated its advantage in the direction of arrival (DOA) estimation. However, it requires a lot of computational cost to iteratively estimate the SBL hyperparameters from measurement data.
Xiang Pan +5 more
doaj +1 more source
Observation of the anisotropy in arrival direction of Cosmic Rays with IceCube
The IceCube Neutrino Observatory is a kilometer-scale detector currently under construction at the South Pole. In its final configuration the detector will comprise 5160 Digital Optical Modules (DOMs) deployed on 86 strings between 1.5-2.5 km deep within
Toscano, S.
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Direction of arrival measurements at UHF
Direction of arrival measurements have been made at 870 MHz in an urban environment. Examples are given showing the multipath components arriving at the receiver after reflection and scattering from buildings. A synthetic aperture technique is used to measure the directions of arrival.
P.A. Matthews, B. Mohebbi
openaire +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

