Results 111 to 120 of about 1,078,062 (309)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The relationship between child and parent anxiety : assessing direction of change during a CBT-based intervention

, 2014
textThis document proposes a study to ascertain if a relationship exists between levels of child and parent anxiety symptoms during an intervention designed to decrease anxiety in youth.
Banneyer, Kelly Nicole
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Schematic illustration of the development of the microbiome in pigs through the initial exposure, transitional, and stable phases, with phase related factors and indication of direction of change in bacterial phyla and diversity (modified from [8–10]).

Schematic illustration of the development of the microbiome in pigs through the initial exposure, transitional, and stable phases, with phase related factors and indication of direction of change in bacterial phyla and diversity (modified from [8–10]).
Sanni Kivinen (18509979), Paulina Heponiemi (18509976), Jaakko Räkköläinen (18509982), Anna Valros (6948140), Maria Carmen Collado (5932082), Emilia König (18509970), Tuomas Borman (18509985), Virpi Piirainen (18509988), Shea Beasley (18509973), Mari Heinonen (2803492), Seppo Salminen (330540), Leo Lahti (61006)   +11 more
core   +1 more source

Scientific and common names, proportion of samples with positive catch, mean overall density, and directional change for species or families, including those from northern, southern, or local (Middle Atlantic Bight) origin (where known), that exhibited significant (p<0.05) change in occurrence over time (blank cells under the Direction of Change column indicate no trend).

, 2019
Scientific and common names, proportion of samples with positive catch, mean overall density, and directional change for species or families, including those from northern, southern, or local (Middle Atlantic Bight) origin (where known), that exhibited ...
Jason M. Morson (7535246), Thomas Grothues (7535249), Kenneth W. Able (3183273)   +2 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Effects of Stimulus Characteristics on Perception of Angular Change

, 1968
A study was made of the effects of 4 variables (stimulus dimension, interstimulus interval, percentage of change, and direction of change) on the accuracy of judgments of size changes in visual angles.
Alfred G. Klipple, Brian E. Schutrumpf
core   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Endogenous Growth, Temporary Equilibrium, and the Direction of Change

This article studies the long-run direction of technological change in an endogenous growth model. Development is modeled as a sequence of temporary equilibria in an overlapping generations framework.
Peter Funk
core