Results 71 to 80 of about 865,492 (315)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

The Mechanism of Direction

Science, 1883
n ...
openaire   +5 more sources

Language and the Moving Body: Directive Actions With the Finnish kato “look” in Nature-Related Activities

Frontiers in Psychology, 2021
The article explores how social interaction is accomplished through intertwined verbal and bodily conduct, focusing on directive actions that include a second-person imperative form of the Finnish verb katsoa “to look,” typically kato. The study draws on
Pauliina Siitonen, Mirka Rauniomaa, Tiina Keisanen   +2 more
doaj   +1 more source

Fulmar Litter EcoQO Monitoring in the Netherlands 1979-2008 in relation to EU Directive 200/59/EC on Port Reception Facilities [PDF]

, 2010
Operational and cargo related wastes from ships are an important source of litter in the marine environment in the southern North Sea and cause serious economical and ecological damage.
Franeker, J.A., van
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

COST-BENEFIT ANALYSIS IN THE NEW LEGISLATION ON ENERGY EFFICIENCY [PDF]

Strategii Manageriale, 2015
In this paper the author presents some aspects of a more comprehensive analysis on the macroeconomic effects it generates new regulations on energy efficiency in the European Union.
Mihaela, IONESCU-SAS
doaj  

European Union Renewable Energy Strategy

Вестник Кемеровского государственного университета, 2022
The renewable energy sector is becoming increasingly important in the global energy balance. This process can be explained by the depletion of fossil resources and the global environmental concern.
E. A. Zharonkina, A. A. Goltseva
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Multilingual Legislation in the European Union. EU and National Legislative-Language Styles and Terminology [PDF]

, 2011
One approach is to consider a specific piece of EU text in a range of languages and consider how the text is reproduced in each language in terms of structure and terminology.
Robertson, Colin
core   +2 more sources