Results 91 to 100 of about 14,576 (298)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Directional GPS antenna for indoor positioning applications [PDF]

open access: yes, 2009
In this paper, a directional GPS antenna for L1 frequency - 1575 MHz - with RHCP and a high directive gain is proposed for indoor positioning applications.
Ozsoy, Kerem   +3 more
core  

Radiation from elementary sources in a uniaxial wire medium

open access: yes, 2012
We investigate the radiation properties of two types of elementary sources embedded in a uniaxial wire medium: a short dipole parallel to the wires and a lumped voltage source connected across a gap in a generic metallic wire. It is demonstrated that the
J. Brown   +6 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

NRI-TL Metamaterial Leaky-Wave Antenna With Off-Broadside Zero Beam-Squinting

open access: yesIEEE Access
Presented is the analysis and design of a leaky-wave antenna (LWA) that radiates an off-broadside beam with zero beam-squinting (ZBS), operating at a frequency of 5.5 GHz.
Kyriakos Neophytou   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Dect architecture proposal for a construction site [PDF]

open access: yes, 1996
A construction site is an specific environment where important propagation related issues have to be considered. In particular an important problem concerns the coverage of buildings under construction and therefore continuously changing.
Agustí Comes, Ramon   +1 more
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Estimation of dielectric constant for various standard materials using microstrip ring resonator [PDF]

open access: yes, 2017
Microstrip ring resonator (MRR) is known for dielectric constant determination and many studies used Teflon as a standard sample. However, there are many other materials available which able to perform better or equivalence as the Teflon in calibrating ...
Abbas, Zulkifly   +3 more
core   +1 more source

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