Results 71 to 80 of about 1,601,243 (284)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Integration of the EU Consumer Credit Market: Proposal for a More Efficient Regulatory Model. CEPS Working Documents No. 213, 1 November 2004 [PDF]
, 2004 Since the adoption of the current Consumer Credit Directive 87/102/EC in 1986, the EU consumer credit market has changed significantly in terms of size and structure. Although amendments were introduced in 1990 and 1999, the Directive no longer addresses
Lannoo, Karel +1 more
core
Overview of Compliance with the Requirements of Directive (EU) 2019/1 with Regard to the Independence and Resources of National Competition Authorities: The Examples of France and Poland. [PDF]
IIC Int Rev Ind Prop Copyr Law, 2022 Piszcz A, Grynfogel C.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EU-welfare legislation on pigs [PDF]
, 2010 An inventory was performed of 1) the present situation regarding the implementation of Directive 2008/120/EC and 2) national government funded research related to the Directive.
Vermeij, I. +3 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Accounting policy in Latvia – existing main rules and current trends
Buhalterinės Apskaitos Teorija ir Praktika, 2014 The article reflects the study on the main aspects of the Directive of the European Parliament and of the Council 2013/34 / EU “On annual financial reports, consolidated financial reports and related reports of enterprises of certain types” (hereinafter ...
Inga Bumane
doaj +1 more source