Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Preferences for end-of-life care in geriatric trauma surgery patients with immobilising fractures - a prospective cohort study. [PDF]
BMC GeriatrKetter V +6 more
europepmc +1 more source
Proposal for a Council Directive on the roadside inspection of the roadworthiness of commercial vehicles circulating in the Community. COM (98) 117 final, 11 March 1998 [PDF]
, 1998 core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Identification and determination of synthetic colors in fine bakery wares (cakes) sold in Riyadh City, Saudi Arabia: a comparative study of the specifications set by the Gulf standardization organization and the European Union. [PDF]
Front NutrAl Fayez MM +5 more
europepmc +1 more source
REPORT FROM THE COMMISSION TO THE COUNCIL AND THE EUROPEAN PARLIAMENT Quality of petrol and diesel fuel used for road transport in the European Union: Fifth annual report (Reporting year 2006). COM (2008) 799 final, 01.12.2008 [PDF]
, 2008 core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Determining intolerable suffering in the context of advance requests for medical assistance in dying. [PDF]
CMAJHolland T, Moreau M.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Agricultural biotechnology in the courts: judicial opinions and commentary. [PDF]
Front Bioeng BiotechnolKershen DL.
europepmc +1 more source