Results 81 to 90 of about 3,094,221 (290)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
DIRECTIVE SPEECH ACTS REALIZATION OF INDONESIAN EFL TEACHER
English Review: Journal of English Education, 2015 This research examines the types and functions of directive speech act performed by an Indonesian EFL teacher in one senior high school in Kuningan, Indonesia. This study uses qualitative method.
Cucu Suhartini, Yulianti Wulansari
doaj
Prasasti: Journal of Linguistics, 2016 Translating utterances is not similar to translating sentences. It requires special attention as there is an intended meaning or message transferred by a speaker to a hearer.
Irta Fitriana
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
A DIRECTIVE SPEECH ACT ANALYSIS IN THE “ENDERS’S GAME” MOVIE BY GAVIN HOOD [PDF]
, 2020 Nadhifatul Mufidah. Register Number Student: 17203163162. 2020. A Directive Speech Act Analysis in The “Enders’s Game” Movie by Gavin Hood. Thesis. English Educational Program. State Islamic Institute (IAIN) of Tulungagung. Advisor: Dr. Erna Iftanti, S.S.
NADHIFATUL MUFIDAH, 172031636162
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Bahastra, 2017 Using advertising as a persusif medium is a relative effective way to convey informations. Tells reader how ads or advertisement of speech may also affect consumer, this making consumer interested in buying the products offered.
Hasmi Novianti
doaj +1 more source