Results 141 to 150 of about 323,551 (282)

Prácticas de dirección y liderazgo en las escuelas primarias públicas de México. Los primeros años en el puesto [PDF]

open access: yes, 2010
Este trabajo es un informe parcial del análisis de las prácticas de dirección y liderazgo de los nuevos directores de escuelas primarias públicas en México.
García-Garduño, José María   +2 more
core   +2 more sources

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

open access: yesAdvanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi   +21 more
wiley   +1 more source

Periódicos de Oporto, públicos de la ciudad : la construcción de la identidad editorial y las audiencias [PDF]

open access: yes, 2013
The three Oporto daily newspapers O Comércio do Porto, O Primeiro de Janeiro and Jornal de Notícias were founded during the XIX century and steadily grew in prestige and respect amongst the national Portuguese press.
Lima, Helena
core  

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

Competition Between Liquid‐Liquid Crystalline Phase Separation (LLCPS) and Liquid‐Liquid Phase Separation (LLPS) in Amyloid Fibril Colloidal Systems

open access: yesAdvanced Science, EarlyView.
This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
wiley   +1 more source

[Online surgical education adopted among urology residency programs in response to COVID-19: A pilot study]. [PDF]

open access: yesActas Urol Esp, 2022
Connelly ZM   +9 more
europepmc   +1 more source

Critical Limitations in Cryogenic Laser Cooling of Solids: Symmetry‐Related Fluorescence Trapping and Condensation‐Induced Parasitic Heating

open access: yesAdvanced Science, EarlyView.
This study uncovers two overlooked bottlenecks in cryogenic laser cooling of solids: symmetry‐driven fluorescence trapping and water vapor condensation. We demonstrate that breaking sample symmetry enhances fluorescence escape, while condensation dominates parasitic heating below 135 K.
Biao Zhong   +5 more
wiley   +1 more source

Origin and historic development of the pedagogic press of Badajoz

open access: yesHistoria de la Educación, 2013
The educational press is one of the media that has most influenced the teachers of Badajoz and their province; however, studies regarding the press of the region have not dealt with this type of publication, even though it is a topic of fundamental ...
Carmelo REAL APOLO
doaj  

A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model

open access: yesAdvanced Science, EarlyView.
We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren   +6 more
wiley   +1 more source

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