Results 171 to 180 of about 172,877 (277)

Sensitivity analysis for generalized estimating equation with non‐ignorable missing data

open access: yesScandinavian Journal of Statistics, EarlyView.
Abstract Many incomplete‐data statistical inference procedures are developed under the missing at random (MAR) assumption. However, the MAR assumption has been criticized as being overly strong for real‐data problems, and is unverifiable by using observed data. To handle data that are missing not at random (MNAR), sensitivity analysis has been proposed
Hui Gong, Kin Wai Chan
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Impact of Omecamtiv Mecarbil (OM) on in‐silico models of heart failure. A mathematical electromechanical model of human ventricular tissue is used to simulate the effects of OM in heart failure with reduced ejection fraction (HFrEF).
Maria Teresa Mora   +8 more
wiley   +1 more source

Enhancing pandemic surveillance and testing: a simulation modeling study utilizing german multicenter data with federated machine learning. [PDF]

open access: yesHealth Care Manag Sci
Kempter S   +8 more
europepmc   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic   +4 more
wiley   +1 more source

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