Results 81 to 90 of about 1,936,656 (285)
Advanced Science, EarlyView.A novel drug‐loaded D/P‐g‐PSB nanogel‐incorporated hydrogel by the electrostatic attraction‐driven self‐assembling process. Sequential drug releasing property (melatonin is released first by physical diffusion, and then ibuprofen is released as the charge shielding effect and hydrogel degradation). This ion‐sensitive hydrogel platform with sequentially
Zhijian Wei +13 more
wiley +1 more source
Prawo Budżetowe Państwa i Samorządu, 2014 Disabled persons conducting non-agricultural economic activity may apply for the refund of social insurance contributions from the State Fund for Rehabilitation of the Disabled Persons.
Marzena Szabłowska-Juckiewicz
doaj +1 more source
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome
Advanced Science, EarlyView.Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel +19 more
wiley +1 more source
Home Automation Control with Multi-modal Interfaces for Disabled Persons [PDF]
, 2014 Hee‐Dong Park
openalex +1 more source
Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance
Advanced Science, EarlyView.Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar +7 more
wiley +1 more source
To what extent does the Paralympic Games promote the integration of disabled persons into society?
The International Sports Law Journal, 2020 C. L. Goh
semanticscholar +1 more source
Advanced Science, EarlyView.Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang +18 more
wiley +1 more source
Advanced Science, EarlyView.It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li +9 more
wiley +1 more source
Hearing loss prevalence and burden of disease in China: Findings from provincial-level analysis
Chinese Medical Journal. Background:. Without timely and effective rehabilitation, hearing loss may profoundly affect human life quality. China has a large population of hearing-impaired individuals, which imposes a heavy health burden on society. Moreover, this population is
Yu Wang +15 more
doaj +1 more source