Results 41 to 50 of about 48,464 (301)

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao   +12 more
wiley   +1 more source

The cumulative effect of economic news in the media: patterns of faith and disappointment

open access: yesRUDN Journal of Studies in Literature and Journalism, 2023
On the example of three thematic layers, the specifics of the presentation of economic ideas in media publications and the transformation of the approach to these ideas over time are considered.
Dmitry E. Konoplev
doaj   +1 more source

Expectation in expressions of disappointment [PDF]

open access: yes, 2021
The research looks into the role of expectations behind expressions of ...
Fangming Cui
core   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

open access: yesAdvanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang   +13 more
wiley   +1 more source

Working towards utopia: hope and disappointment in a room of one's own [PDF]

open access: yes
In this paper, three women writers offer a personal and critical consideration of the utopian ideal of a place to write – Woolf’s pervasive ‘room of one’s own’ (1977) – as both a physical location and a psychological and cultural ‘space’. In doing so, we
Sulway, Nike, Arena, Maria, East, Tara
core   +1 more source

Experimentation and Disappointment [PDF]

open access: yes, 2003
We depart from the classic setting of bandit problems by endowing the agent with a disappointment-elation utility function. The disutility of a loss is assumed to be greater than the elation associated with same-size gain, according to Kahneman-Tversky ...
Luppi, Barbara
core   +1 more source

Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang   +6 more
wiley   +1 more source

Perceptions of Referendums and Democracy: The Referendum Disappointment Gap

open access: yesPolitics and Governance, 2019
We examine the gap between perceptions of seeing referendums as an important democratic principle, versus perceiving how referendums are used in practice. We term this the “referendum disappointment” gap.
Shaun Bowler, Todd Donovan
doaj   +1 more source

Farmers’ Protests in Germany: Media Coverage and Types of Bias

open access: yesAgribusiness, EarlyView.
ABSTRACT The German farmers’ protests of 2024 sparked widespread media coverage and public debate. Yet, media coverage was not always positive, reflecting the media's attention‐seeking and selective focus. Occurrences of farmers blocking media outlets reflected distrust in how their concerns were portrayed.
Felix Schlichte, Doris Läpple
wiley   +1 more source

Disappointment and disgust, or teaching? [PDF]

open access: yes, 2005
Is 'disappointment' and 'the teaching of disgust' the core of TV Studies? Or might teaching better be accomplished by inspiring positive civic action. Either way, doesn't reality TV do it better? John Hartley uses examples from reality TV to discuss this
Hartley, John
core  

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