Results 21 to 30 of about 14,134 (184)

The US Initiative on Creating an Environment for Nuclear Disarmament

open access: yesJournal for Peace and Nuclear Disarmament, 2020
The purpose of this paper is to examine and critically evaluate a new US initiative called Creating an Environment for Nuclear Disarmament (CEND), which was launched in 2018.
Mitsuru Kurosawa
doaj   +1 more source

Verification of DPRK Nuclear Disarmament: The Pros and Cons of Non-Nuclear-Weapon States (specifically, the ROK) Participating in This Verification Program

open access: yesJournal for Peace and Nuclear Disarmament, 2019
In the expert and diplomatic communities, it is generally considered that disarmament verification should be undertaken as far as possible on a multilateral basis.
John Carlson
doaj   +1 more source

The Nuclear Disarmament Cases: Is Formalistic Rigour in Establishing Jurisdiction Impeding Access to Justice?

open access: yesUtrecht Journal of International and European Law, 2017
Nuclear disarmament falls within the purview of the purposes envisaged in Article 1 of the United Nations Charter. The International Court of Justice (ICJ) in 1996 delivered an advisory opinion on legality of use of nuclear weapons and has stated that ...
Meenakshi Ramkumar, Aishwarya Singh
doaj   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

No First Use: How to Overcome Japan’s Great Divide

open access: yesJournal for Peace and Nuclear Disarmament, 2018
In Japan, there is strong support for nuclear disarmament and a no nuclear first use policy. The benefits of a no first use policy in promoting nuclear disarmament and nonproliferation and in preventing the start of a nuclear war by accident or by ...
Nobuyasu Abe
doaj   +1 more source

The Guterres Disarmament Agenda and the Challenge of Constructing a Global Regime for Weapons

open access: yesJournal for Peace and Nuclear Disarmament, 2020
On 24 May 2018, United Nations Secretary-General António Guterres launched his new “disarmament agenda” in an address at the University of Geneva.
Randy Rydell
doaj   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

open access: yesAdvanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie   +24 more
wiley   +1 more source

Phosphonomethyl (Thio)Phosphonamidite Reagents for the Construction of Phosphonylmethyl Phosphono(Di)Thioate Mono‐ and Diesters

open access: yesChemistry – A European Journal, EarlyView.
A set of new phosphonomethyl (thio)phosphonamidite reagents is introduced to generate unprecedented pyrophosphate mimetics. The versatile P(III)‐P(V) reagents allow for the construction of various pyrophosphate isosteres, and the applicability of the chemistry is illustrated in the assembly of a diverse set of stabilized CDP‐glycerol and CDP‐ribitol ...
Pascal Balić   +4 more
wiley   +1 more source

Australia and the Non-Proliferation and Disarmament Initiative: difficult times for disarmament diplomacy [PDF]

open access: yes, 2013
Australia recognises the critical role that the Treaty on the Non-Proliferation of Nuclear Weapons plays in preventing uncontrolled proliferation and promoting disarmament, and upholding the treaty has long been a core foreign policy goal.
Tanya Ogilvie-White
core  

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