Results 181 to 190 of about 1,312,076 (297)

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

open access: yesAdvanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao   +11 more
wiley   +1 more source

Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery

open access: yesAdvanced Science, EarlyView.
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le   +5 more
wiley   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

open access: yesAdvanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie   +10 more
wiley   +1 more source

Tackling disasters… Are we prepared?

open access: yesIndian Journal of Community Medicine, 2015
Farha Yesmin, Rupali Baruah
openaire   +3 more sources

Let’s Prepare for Disasters

open access: yesJOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE, 2021
openaire   +2 more sources

Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades

open access: yesAdvanced Science, EarlyView.
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo   +2 more
wiley   +1 more source

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