Results 191 to 200 of about 271,999 (308)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen   +8 more
wiley   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

open access: yesAdvanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong   +6 more
wiley   +1 more source

Ion Superhighways in a Hierarchical Polymer‐Ceramic Membrane Enable Rapid and Selective Lithium Extraction

open access: yesAdvanced Science, EarlyView.
A flexible PDMS‐LATP polymer‐ceramic membrane creates lithium‐ion “superhighways” for rapid and selective extraction from complex brines. The amorphous PDMS matrix suppresses nonselective leakage and stabilizes the ceramic network, while LATP provides preferential Li+ conduction.
Xinxin Wei   +12 more
wiley   +1 more source

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

open access: yesAdvanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song   +8 more
wiley   +1 more source

Stabilized Cubic GeTe With Matched Grain‐Boundary Networks and Band Convergence for High‐Performance Dual‐Mode Thermoelectric Devices

open access: yesAdvanced Science, EarlyView.
I‐doping stabilizes the cubic phase of GeTe and generates “electron‐transparent, phonon‐blocking” grain boundary networks while inducing valence‐band convergence. This synergistic structural‐electronic design enables effective electron‐phonon decoupling, achieving an exceptional average zTave of ∼1.62, a peak zT of ∼2.2, and enhanced mechanical ...
Xiaobo Tan   +10 more
wiley   +1 more source

Technological Disasters

open access: yes
Accidents or disasters can be the result of natural or man-made disasters. Technological disasters, civil commotion, terror acts and armed conflicts are regarded as man-made disasters.
Jemeļjanovs, Vladimirs   +2 more
core  

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