Results 121 to 130 of about 199,229 (299)

Calcium leaching in hydraulic concrete: experimental and numerical study on pore evolution and phase dissolution

Results in Engineering
In this study, the calcium leaching behavior in hydraulic concrete under aggressive environments was systematically investigated. Concrete specimens with water-to-binder ratios of 0.45 were subjected to accelerated leaching in 6 mol/L NH4Cl solutions ...
Chunmeng Jiang, Shihao An, Cheng Chen, Li Xia, Jingwei Gong, Haibo Jiang   +5 more
doaj   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Hydraulic performance of a portable triangular-central flume for rectangular channels

Guan'gai paishui xuebao
【Objective】Accurate measurement of channel flow is essential for effective irrigation district management. This study evaluates the hydraulic performance of a portable triangular-central flume for measuring water flow in rectangular channels.
GUO Xingchen, YUAN Changcong, WANG Fuyou, MAHEMUJIANG·Aihemaiti, JIN Peng, LI Junbo, TAO Hongfei   +6 more
doaj   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Integrated seismo-geodetic observatory network for monitoring the Lembang Fault, West Java, Indonesia

Earth and Planetary Physics
The Lembang Fault is a major geological feature in West Java that borders the northern edge of Bandung (one of Indonesia’s largest cities). It lies just south of the active Tangkuban Perahu Volcano, exhibiting clear geomorphic signs of recent activity ...
Nuraini Rahma Hanifa, Endra Gunawan, Dini Nurfiani, Achmad Fakhrus Shomim, Faiz Muttaqy, Aang Gunawan Sutyawan, Lina Handayani, Deasy Arisa, Rian Amukti, Muhammad Hanif, Yayat Sudrajat, Dannie Hidayat, Iwan Hermawan, Agus Men Riyanto, Eko Yulianto, Adrin Tohari, Qori'atu Zahro, Atin Nur Aulia, Juniator Tulius, Sri Widiyantoro, Rachmah Ida, Cecep Pratama, Ridwan Suhud, Putri Natari Ratna, Titi Anggono   +24 more
doaj   +1 more source

Minimizing the disaster risk in optical telecom networks [PDF]

, 2012
De Leenheer, Marc, Dikbiyik, Ferhat, Mukherjee, Biswanath, Reaz, Abu S   +3 more
core   +2 more sources

Ultrastrong TEMPO‐Oxidized Densified Bamboo via Interface Decoupling and Hierarchical Toughening

Advanced Science, EarlyView.
This study develops TEMPO‐oxidized densified bamboo that achieves ultrahigh strength and toughness by decoupling rigid hydrogen bonds into reversible van der Waals interactions. TEMPO oxidation reorganizes the cellulose hydrogen‐bonding network, facilitating energy dissipation via reversible interactions, thereby establishing a general strategy to ...
Ziyu Ba, Hongyun Luo, Jie Cui, Juan Guan, Zhaoliang Guo, Robert O. Ritchie   +5 more
wiley   +1 more source

Changes in future drought characteristics in the Ili River Basin, China, using the new comprehensive standardized drought index

Ecological Indicators
The construction of a comprehensive drought index and the evaluation of future drought characteristics are important for drought management decisions.
Zilong Li, Zhenxia Mu, Xiaoyan Qiu, Jing Liu   +3 more
doaj   +1 more source