Results 31 to 40 of about 197,606 (282)
Disaster risk reduction measures n Bangladesh [PDF]
, 2012 Disasters damage the entire economy of the country when they predominantly take place in developing countries. While no country in the world is entirely safe, lack of capacity to limit the impact of hazards has made developing countries being the most ...
Amaratunga, Dilanthi +4 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Excavation compensation theory and supplementary technology system for large deformation disasters
Deep Underground Science and Engineering, 2023 Given the challenges in managing large deformation disasters in energy engineering, traffic tunnel engineering, and slope engineering, the excavation compensation theory has been proposed for large deformation disasters and the supplementary technology ...
Manchao He, Qiru Sui, Zhigang Tao
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Redai diliBike-sharing has emerged as a crucial mode of short-distance transportation for urban residents due to its flexibility, convenience, and affordability. This paper analyzes the spatiotemporal data of bike-sharing in the central urban area of Shenzhen to ...
Zheng Jixiang +5 more
doaj +1 more source
Principles for management of risks of critical infrastructure [PDF]
, 2018 On the basis of present knowledge, the critical infrastructure is a set of physical (technical and material), cyber and organizational subsystems of human system that are necessary for ensuring the protection of: human lives, health and security ...
Procházka J. +2 more
core
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Research Directions in Information Systems for Humanitarian Logistics [PDF]
, 2011 This article systematically reviews the literature on using IT (Information Technology) in humanitarian logistics focusing on disaster relief operations. We first discuss problems in humanitarian relief logistics.
Hillegersberg, Jos van +1 more
core +1 more source
The 1935 Hsinchu-Taichung Earthquake [PDF]
, 2020 The history of natural disasters in Taiwan has frequently been linked to the practice of historical preservation, archival science, oral history, and museum curatorship.
Alsford, Niki J.P.
core +2 more sources