Results 91 to 100 of about 1,196,992 (295)

On the Bardeen-Petterson Effect in black hole accretion discs

, 2015
We investigate the effect of black hole spin on warped or misaligned accretion discs - in particular i) whether or not the inner disc edge aligns with the black hole spin and ii) whether the disc can maintain a smooth transition between an aligned inner ...
Nealon, Rebecca, Nixon, Chris, Price, Daniel   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Urban CGE Modeling: An Introduction [PDF]

Cities are usually confronted with a large variety of economic development choices. With growing environmental concern as well as rising income and wealth inequalities, assessment of the impacts of such choices is likely to gain in importance ...
Julia Lechner
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Analysis of transitional stresses in non-local thermo-elastic disc under steady state temperature

International Journal of Applied Mechanics and Engineering
In solid mechanics, there are various applications of non-local theories in wave propagation, size effects, surface effects, and understanding interactions of composite materials.
Praveen Ailawalia, Ajay Bhiwal, Jatinder Kaur, Paweł Jurczak   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Accretion Disc Wind Variability in the States of the Microquasar GRS 1915+105

, 2011
Continuing our study of the role and evolution of accretion disc winds in the microquasar GRS 1915+105, we present high-resolution spectral variability analysis of the beta and gamma states with the Chandra High Energy Transmission Grating Spectrometer ...
Andrew J. Petschek, Begelman, Belloni, Belloni, Blum, Brandt, Canizares, Draine, Ebisawa, Eikenberry, Fender, Fender, Fender, Fender, Frank, Hannikainen, Houck, Houck, Joseph Neilsen, Julia C. Lee, Kallman, Kallman, Klein-Wolt, Kotani, Kotani, Lee, Luketic, Markwardt, Meier, Migliari, Mikles, Miller, Miller, Miller, Miller, Miller, Mirabel, Mirabel, Nayakshin, Neilsen, Neilsen, Ponti, Pooley, Proga, Proga, Reynolds, Rodriguez, Rodriguez, Rothstein, Schulz, Shields, Soleri, Steiner, Tagger, Ueda, Ueda, Ueda, Verner, Wilms, Xiang, Zdziarski, Zimmerman, Życki   +62 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Modelling the high mass accretion rate spectra of GX 339-4: Black hole spin from reflection?

, 2011
We extract all the XMM-Newton EPIC pn burst mode spectra of GX 339-4, together with simultaneous/contemporaneous RXTE data. These include three disc dominated and two soft intermediate spectra, and the combination of broad bandpass/moderate spectral ...
Ballantyne, Chris Done, Davis, Done, Done, Done, Done, Done, Dunn, Fabian, Freyberg, Gierliński, Guainazzi, Kirsch, Kolehmainen, Kubota, Kubota, Kubota, Laor, Li, Mari Kolehmainen, María Díaz Trigo, Miller, Miller, Miller, Miller, Miller, Mitsuda, Reis, Ross, Ross, Steiner, Steiner, Weisskopf, Yamada, Życki   +35 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source