Results 101 to 110 of about 1,617,242 (349)

SECCA procedure for anal incontinence and antibiotic treatment: a case report of anal abscess

open access: yesBMC Surgery, 2018
Background Fecal Incontinence (FI) can seriously affect quality of life. The treatment of fecal incontinence starts conservatively but in case of failure, different surgical approaches may be proposed to the patient.
Francesca Mandolfino   +5 more
doaj   +1 more source

Housing Cooperatives and Social Capital: The Case of Vienna [PDF]

open access: yes
Drawing on the case of Vienna, the article examines the role of third sector housing for social cohesion in the city. With the joint examination of an organisational and an institutional level of housing governance, the authors apply an interdisciplinary,
Andreas Novy, Richard Lang
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Motives and influencing factors of corporate regional engagement: industry and company specific patterns [PDF]

open access: yes
Traditionally, regional endowments are viewed as external variables when it comes to location choices of companies. In most concepts on location choices and regional economics companies are thought to view the local labour market, the local innovation ...
Eva Nussmüller   +2 more
core  

The evolution of a supermassive binary caused by an accretion disc

open access: yes, 1998
The interaction of a massive binary and a non-self-gravitating circumbinary accretion disc is considered. The shape of the stationary twisted disc produced by the binary is calculated.
A. G. Polnarev   +40 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Optic Disc and Optic Cup Segmentation Methodologies for Glaucoma Image Detection: A Survey

open access: yesJournal of Ophthalmology, 2015
Glaucoma is the second leading cause of loss of vision in the world. Examining the head of optic nerve (cup-to-disc ratio) is very important for diagnosing glaucoma and for patient monitoring after diagnosis.
A. Almazroa   +3 more
semanticscholar   +1 more source

Competencies of firms, external knowledge sourcing and types of innovation in regions of Europe [PDF]

open access: yes
Many innovation studies have been focusing on a narrow concept of innovation such as the generation of patents or new products. The performance of companies, however, often depends on innovation defined from a broader perspective.
Christoph Höglinger   +2 more
core  

Polar bulges and polar nuclear discs: the case of NGC 4698

open access: yes, 2012
The early-type spiral NGC 4698 is known to host a nuclear disc of gas and stars which is rotating perpendicularly with respect to the galaxy main disc. In addition, the bulge and main disc are characterised by a remarkable geometrical decoupling.
A. Beifiori   +43 more
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

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