Results 121 to 130 of about 1,303,041 (346)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Polar bulges and polar nuclear discs: the case of NGC 4698

, 2012
The early-type spiral NGC 4698 is known to host a nuclear disc of gas and stars which is rotating perpendicularly with respect to the galaxy main disc. In addition, the bulge and main disc are characterised by a remarkable geometrical decoupling.
A. Beifiori, A. Pizzella, Bertola, Bertola, Bertola, Bertola, Boissier, Cappellari, Coccato, Corsini, de Vaucouleurs, E. Dalla Bontà, E. M. Corsini, F. Bertola, Falcón-Barroso, Fathi, Freedman, Hambly, Hartmann, Holtzman, Hopkins, J. Méndez-Abreu, Kassin, Kormendy, Krajnović, Krist, L. Morelli, Lawrence, Ledo, Lindblad, Matthews, McMaster, Morelli, Morelli, Méndez-Abreu, Möllenhoff, N. Pastorello, Pignatelli, Pizzella, Prantzos, Sarzi, Sarzi, Scorza, Zaritsky   +43 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Antibiotic Prescription for the Prevention of Postoperative Complications After Third-Molar Extractions: A Systematic Review

Dentistry Journal
Background: Third-molar extractions are common procedures often complicated by infections and alveolitis. The use of antibiotics as prophylaxis to prevent these complications is debated due to potential risks and side effects.
Nicola De Angelis, Lorenzo Denegri, Ioana Cristina Miron, Catherine Yumang, Paolo Pesce, Domenico Baldi, Francesca Delucchi, Francesco Bagnasco, Maria Menini   +8 more
doaj   +1 more source

Partial recovery from severe trauma-induced paralysis after lumbar disc herniation

, 2022
Xiaozhe Zhou, Lingnan Zhang, Wenshan Gao
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Volumetric star formation laws of disc galaxies [PDF]

, 2018
Cecilia Bacchini, Filippo Fraternali, Giuliano Iorio, Gabriele Pezzulli   +3 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Thickness variation parameter in a thin rotating disc by finite deformation [PDF]

FME Transactions, 2013
Seth’s transition theory is applied to the problems of thickness variation parameter in a thin rotating disc by finite deformation. Neither the yield criterion nor the associated flow rule is assumed here.
Pankaj Thakur, Singh S.B., Jatinder Kaur
doaj