Results 131 to 140 of about 1,303,041 (346)
Edge notched disc test for evaluation of mode-I fracture toughness of brittle material
, 2023 Hadi Haeri +6 more
openalex +1 more source
Perturbed distribution functions with accurate action estimates for the Galactic disc [PDF]
, 2021 H. Al Kazwini +10 more
openalex +1 more source
Q criterion for disc stability modified by external tidal field [PDF]
, 2013 The standard Q criterion (with Q > 1) describes the local stability of a disc supported by rotation and random motion. Most astrophysical discs, however, are under the influence of an external gravitational field which can affect their stability.
Jog, Chanda J.
core
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Two-dimensional transient problem for a thick disc with internal heat source [PDF]
FME Transactions, 2010 The problem treated here is to determine thermo-elastic stress in a thick disc due to interior heat generation within the solid, under thermal boundary condition, which is subjected to arbitrary initial temperature on the upper and lower face at zero ...
Vargeze Vinod, Kalsa Lalsing
doaj
Evaluation of Lumbar Intervertebral Disc Degeneration Using T1ρ and T2 Magnetic Resonance Imaging in a Rabbit Disc Injury Model [PDF]
, 2018 Tetsuhiro Ishikawa +6 more
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source