Customized extracellular vesicles targeting lysosomal biogenesis deliver therapeutic cargo for intervertebral disc degeneration treatment. [PDF]
J NanobiotechnologyLiao Z, Ou Z, Tong B, Li S, Yang C.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Case Report: Endoscopic cystectomy vs. lumbar interbody fusion for liquid- and gas-filled discal cysts: a case series and literature review. [PDF]
Front SurgHuang H, Li G, Deng J, Chen R, Zhou Y.
europepmc +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Exploring the relationship between clinical symptoms and MRI findings in temporomandibular joint disorders: a preliminary study. [PDF]
J Oral Facial Pain HeadacheSancar E +5 more
europepmc +1 more source
Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source
A Comparison of Retinal Nerve Fiber Layer Thickness and Bruch's Membrane Opening-Minimum Rim Width Thickness Between Glaucoma and Disc-Suspect Patients Using Optical Coherence Tomography. [PDF]
CureusSidana A, Sen S, Das M.
europepmc +1 more source
Quantitative Assessment of Upper Limb Ataxia Using a Virtual Reality‐Based Evaluation System
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebellar ataxia impairs coordination and balance, reducing quality of life. Conventional clinical scales, including the Scale for the Assessment and Rating of Ataxia (SARA) and the International Cooperative Ataxia Rating Scale (ICARS), are widely used to assess ataxia but are limited by subjectivity and inter‐rater variability ...
Masayuki Sato +5 more
wiley +1 more source
A novel classification and clinical evaluation of various morphologies of calcified lumbar disc herniation treated using unilateral biportal endoscopic technique. [PDF]
J Orthop Surg ResLiu H, Yang X, Wu H, Zhang S, Wang S.
europepmc +1 more source