Results 81 to 90 of about 387,228 (272)
On outflowing viscous disc models for Be stars [PDF]
arXiv, 1999 It is assumed that Be star discs are driven by viscosity. Emission from disc models is calculated and is confronted with continuum observations. It is found that the outflowing viscous disc models can reproduce the observed IR continuum emission.
arxiv
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Two-dimensional transient problem for a thick disc with internal heat source [PDF]
FME Transactions, 2010 The problem treated here is to determine thermo-elastic stress in a thick disc due to interior heat generation within the solid, under thermal boundary condition, which is subjected to arbitrary initial temperature on the upper and lower face at zero ...
Vargeze Vinod, Kalsa Lalsing
doaj
Tidal Truncation of Inclined Circumstellar and Circumbinary Discs in Young Stellar Binaries [PDF]
, 2015 Recent observations have shown that circumstellar and circumbinary discs in young stellar binaries are often misaligned with respect to the binary orbital plane. We analyze the tidal truncation of such misaligned discs due to torques applied to the disc at the Lindblad resonances from the tidal forcings of the binary.
arxiv +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
How external photo-evaporation changes the chemical composition of the inner disc [PDF]
A&A 691, A32 (2024)Stars mostly form in clusters where neighboring stars can influence proto-planetary disc evolution. Besides gravitational interactions, external photoevaporation can shape these discs. Depending on the strength of photoevaporation, discs can be destroyed within 1-2 Myrs or more gradually. We use the chemcomp code, incorporating a viscous disc evolution
arxiv +1 more source