Results 91 to 100 of about 6,639,533 (289)
Pattern Electroretinogram Parameters Are Associated with Optic Nerve Morphology in Preperimetric Glaucoma after Adjusting for Disc Area. [PDF]
J Ophthalmol, 2021 Tirsi A +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Effect of myopia and optic disc area on ganglion cell-inner plexiform layer and retinal nerve fiber layer thickness. [PDF]
Indian J Ophthalmol, 2021 Ganekal S, Sadhwini MH, Kagathur S.
europepmc +1 more source
Covering Area in a Disc by Finitely Many Triangles
The PUMP Journal of Undergraduate ResearchWe consider how to cover the most area inside of a circular disc by using finitely many triangles. Even in simple cases with the number of triangles being small, we do not know what is the maximum area that can be covered. However, as the number of triangles tends to infinity, we use some estimates and existing literature to derive the rate that the ...
Zihao Chen +6 more
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A model of friction for a pin-on-disc configuration with imposed pin rotation [PDF]
, 2011 A friction model is developed by considering the Coulomb friction model, a probabilistic approach of wear prediction, the kinematics of the pin-on-disc configuration and the elastic theory of bending.
Hadfield, Mark +3 more
core +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Measurement of disc parameters.
, 2015 Before the measurement, refraction, corneal curvature, and axial length were entered to the software to adjust for the ocular magnification effect. A) Ovality Index: Longest (1) and shortest (2) diameters of the optic disc were identified and manually ...
Atsuya Miki (795317) +4 more
core +1 more source