Results 91 to 100 of about 260,516 (241)

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui   +10 more
wiley   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella   +5 more
wiley   +1 more source

Analysis and Enlightenment on the Relationships between Two Kinds of Cutter Life Evaluation Indexes and Installation Radius: A Case Study

open access: yesBuildings
Accurate evaluation of cutter life at different cutter positions on the cutter head is helpful to determine the time of cutter change and reduce the time of cutter wear measurement, which is of great significance to improve the tunneling efficiency of ...
Jianping Liu   +4 more
doaj   +1 more source

Disc Cutter Consumptions Prediction on Applying Shield TBM at the Han Riverbed Tunnel

open access: yes, 2010
This study was conducted to estimate the number of disc cutter consumption and to predict amount of disc cutters when a shield TBM(Tunnel Boring Machine) of the Han Riverbed Tunnel was applied. In fact, it is almost impossible to change the machine after
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Optimization of the Disc Cutter Structure Parameters Based on Genetic Algorithm

open access: yes, 2011
In the process of shield tunneling construction, the energy consumption is a prominent issue. The disc cutter blade angle, blade tip width and corner radius are taken as design variables, and the minimum cutting special energy consumption as the target ...
Wen Hua Liu   +4 more
core   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Optimal Design of Disc Cutter Structure Parameter Based on Genetic Algorithm

open access: yes, 2011
Because of the situation that the disc cutter bearing seriously damaged in the cutting process, disc cutter structural parameters is optimized which mainly affect the force on the bearing.
Yi Min Xia   +3 more
core   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

open access: yesArthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk   +7 more
wiley   +1 more source

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