Results 61 to 70 of about 10,655 (303)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih   +40 more
wiley   +1 more source

Design, Meshing Characteristics and Stress Analysis of Cylindrical Gears with Curvilinear Tooth Profile [PDF]

open access: yes, 2016
Curvilinear tooth gears are commonly produced on a face milling cutter and a hob cutter. However, this paper proposes a kind of curvilinear tooth gear which is processed by a parallel linkage with a single blade cutter. For the purpose of identifying the
Xingqiang Tan   +2 more
core   +1 more source

Simulation of low rigidity part machining applied to thin-walled structures [PDF]

open access: yes, 2010
The aim of this study is to evaluate the modelling of machining vibrations of thin-walled aluminium work- pieces at high productivity rate. The use of numerical simulation is generally aimed at giving optimal cutting conditions for the precision and the ...
Arnaud, Lionel   +4 more
core   +4 more sources

Study on Forming Technology of TBM Disc Cutter Ring

open access: yesJournal of Physics: Conference Series, 2019
Abstract The tunnels and underground projects bring an unprecedented development of hard rock tunneling technology. The forming process and material properties of the 20 inch disc cutter ring has been studied by the finite element simulation and test methods.
Yong Hu   +5 more
openaire   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen   +11 more
wiley   +1 more source

Influence of confining stress on different diameters of disc cutters in rock cutting

open access: yesData-Centric Engineering
Tunnel boring machines (TBMs) are essential equipment for tunnel excavation. The main component of TBMs for breaking rock is the disc cutter. The effectiveness and productivity of TBM operations are directly impacted by the disc cutter design and ...
Mohammad Ali Torabi   +2 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Tunneling and Drilling for OTEC Cold Water Pipes [PDF]

open access: yes, 1985
This report summarizes the results of a study to determine the feasibility of using a tunnel or large-diameter drilled shaft as a conduit for transporting cold water from an ocean depth of 2000 ft to an ocean thermal energy conversion (OTEC) plant ...
Energy Technology Engineering Center   +2 more
core  

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