Results 51 to 60 of about 131,362 (294)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Comparison of the Efficacy of Two Protocol Treatments in Patients with Symptomatic Disc Displacement without Reduction: A Randomized Controlled Trial [PDF]
, 2023 André Almeida +5 more
openalex +1 more source
Histologic and Histomorphometric Analysis of Posterior Region of the Human Temporomandibular Disc [PDF]
, 2008 Objective The aim of this study was to analyze histologic and histomorphometric features of the articular disc in groups with and without disc displacement.
Almeida, Luis Eduardo +8 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Cavity optomechanics with ultra-high Q crystalline micro-resonators
, 2010 We present the first observation of optomechanical coupling in ultra-high Q crystalline whispering-gallery-mode (WGM) resonators. The high purity of the crystalline material enables optical quality factors in excess of 10^{10} and finesse exceeding 10^{6}
A. G. Smagin +3 more
core +1 more source
Geometrical and Physical Properties of Circumbinary Discs in Eccentric Stellar Binaries [PDF]
, 2008 In a previous work (Pichardo et al. 2005), we studied stable configurations for circumstellar discs in eccentric binary systems. We searched for "invariant loops": closed curves (analogous to stable periodic orbits in time-independent potentials) that ...
Akeson +71 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Optical encoder code disc displacement measurement [PDF]
, 2011 Запропоновано метод визначення зміщення осі диска оптоелектронного давача кута, який підвищує надійність шляхом раннього виявлення метрологічної відмови ...
Паламар, Михайло Іванович +1 more
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