Results 111 to 120 of about 57,328 (362)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Overactivation of NF-kB pathway can induce apoptosis by down-regulating glycolysis in human degenerative nucleus pulposus cells

Heliyon
Intervertebral disc herniation, a prevalent condition in spinal surgery that frequently results in low back pain and lower limb dysfunction, significantly impacting patients' quality of life.
Pan Tang, Bo Liu
doaj   +1 more source

Reasons for repeated surgical interventions in patients after surgery for spinal disc herniation

Bolʹ, Sustavy, Pozvonočnik, 2019
Background. The article presents a retrospective analysis of the causes of negative results of surgical treatment in elderly people with spinal disc herniation.
V.K. Piontkovsky, І.V. Fishchenko
doaj   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source

Lumbar disc herniation: long-term outcomes after mini-open discectomy [PDF]

, 2019
Tianhang Xie, Xi Yang, Yueming Song
openalex   +1 more source

Association between fetal brain diffusion‐weighted imaging and postnatal neurodevelopmental outcome after prenatal myelomeningocele repair

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Myelomeningocele (MMC) is associated with significant alterations of the brain microstructure, which can impair long‐term neurodevelopmental outcomes. By measuring the random displacement of water molecules within the brain, magnetic resonance imaging (MRI)‐based diffusion‐weighted imaging (DWI) can provide objective metrics, such as
R. Corroenne, T. A. G. M. Huisman, W. E. Whitehead, A. A. Nassr, J. L. Munoz, J. Castillo, H. Castillo, R. M. Johnson, R. V. Donepudi, M. A. Belfort, M. Sanz‐Cortes   +10 more
wiley   +1 more source

INFLUENCE OF FACET TROPISM ON THE LOCATION OF LUMBAR DISC HERNIATION

Coluna/Columna
Objective: To correlate facet tropism with the side and location of the intervertebral disc in which the lumbar disc herniation occurred. Methods: A retrospective descriptive study that evaluated Magnetic Resonance Imaging of 255 patients with lumbar ...
RODRIGO ARNOLD TISOT, JULIANO DA SILVEIRA VIEIRA, DIEGO DA SILVA COLLARES, LEONARDO DOMINGUES STUMM, MARIANO FERABOLI FONTANA, AUGUSTO PASINI, EDUARDO CORONEL, EDUARDO SCHARNOVSKI, MAIARA AGOSTINI, MATEUS BORIN, VICTOR KASPER, VICTOR SÁNCHEZ, WALTER ISERHARD   +12 more
doaj   +1 more source

Herniated disc disease: diagnostics [PDF]

, 2010
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of herniated disc ...
Isaacs, Brandon, Pandya, Nirav
core  

Evaluation of long‐term postoperative morbidity and survival after equine colic surgery using a complication severity classification

Veterinary Record, EarlyView.
Abstract Background Most studies on colic surgery outcome focus on short‐term survival and complications. Long‐term outcomes, particularly post‐discharge morbidity, are poorly characterised despite their relevance. No standardised system has previously integrated both short‐ and long‐term postoperative complications with survival outcomes.
Marco Gandini, Gessica Giusto
wiley   +1 more source