Results 191 to 200 of about 89,243 (282)

Editorial: Social aspects of crop genome editing. [PDF]

Front Genome Ed
Venkataraman S, Hefferon K.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Correction: Psychological Inoculation for Credibility Assessment, Sharing Intention, and Discernment of Misinformation: Systematic Review and Meta-Analysis.

J Med Internet Res
Lu C, Hu B, Li Q, Bi C, Ju XD.
europepmc   +1 more source

The development of media truth discernment and fake news detection is related to the development of reasoning during adolescence. [PDF]

Sci Rep
Lemaire M, Ye S, Le Stanc L, Borst G, Cassotti M.   +4 more
europepmc   +1 more source

Author\u27s Response

, 2009
Bill, J. Brent
core  

The People\u27s Pope: A Gift and a Challenge for the Academic World [PDF]

, 2014
Howell, Patrick, S.J.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The breakthroughs of caregivers in a parent-implemented intervention for children with neurodevelopmental disorders in Hong Kong, China: an exploratory qualitative study of change mechanisms. [PDF]

Front Psychiatry
Wong CHM, Chan CKY, Wong PWC.
europepmc   +1 more source

The \u3cem\u3e Sensus Fidelium\u3c/em\u3e: Discerning the Path of Faith [PDF]

, 2015
Wood, Susan K.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source