Results 41 to 50 of about 207,104 (266)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Experimental study on discharge capacity of street inlet in urban flooding

Shui kexue jinzhan, 2020
Urban flood disasters have occurred frequently in recent years in China, causing a serious threat to urban management and the safety of people and property.
Qian CHEN, Junqiang XIA, Boliang DONG
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Electrodeposited PbO2 Thin Films with Different Surface Structure as Positive Plate in Lead Acid Batteries

International Journal of Electrochemical Science, 2018
PbO2 thin film is essential for applications in lead acid batteries system. In this work, PbO2 thin films with different surface microstructure were fabricated through electrodeposition technique by controlling the deposition current density. Though PbO2
Xuan Zhao, Cheng Li, Yaqiong Wang, Wenlin Xu   +3 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Molten Salt Synthesis of Disordered Spinel LiNi0.5Mn1.5O4 with Improved Electrochemical Performance for Li-ion Batteries

International Journal of Electrochemical Science, 2018
Disordered spinel LiNi0.5Mn1.5O4 (LNMO) was successfully synthesised via a molten-salt method using a mixture of LiOH⋅H2O and LiNO3 salts. The precursor was annealed at 750, 850 or 950 °C for 12 h, and the effects of calcination temperature on the ...
Nabilah Mokhtar, Nurul Hayati Idris, M.F. Md Din   +2 more
doaj   +1 more source

II. On stratified discharges. V. Discharge from a condenser of large capacity [PDF]

Proceedings of the Royal Society of London, 1878
Abstract The principal object of the following communication is to describe an instrumental arrangement which has proved very convenient for the production of steady striæ. The first attempt which was made nearly two years ago (February, 1876), consisted in charging a Leyden battery of nine large jars by means of an induction coil ...
openaire   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Discharge Capacity of Prefabricated Vertical Drain Confined in-clay

Geosynthetics Engineering Journal, 2000
This paper reports the long-term discharge capacities of four types of prefabricated vertical drains (PVDs) confined in clay. The results indicate that under clay confinement, the PVD discharge capacities significantly reduced with time. The discharge capacity reduction may be caused by creep deformation of the PVD filter or clogging of the drainage ...
Miura, N., Chai, J. C.
openaire   +2 more sources