Results 31 to 40 of about 127,309 (291)

Discharge planning practice for patients with colorectal cancer in Thailand

open access: yesNursing Practice Today, 2022
Background & Aim: Nurses play a vital role in discharge planning, especially for patients with colorectal cancer who require complex post-treatment care.
Cherdsak Duangchan   +2 more
doaj   +1 more source

Building Bridges for Indigenous Children’s Health: Community Needs Assessment Through Talking Circle Methodology

open access: yesRisk Management and Healthcare Policy, 2021
Sherri Di Lallo,1 Keren Schoenberger,2 Laura Graham,2 Ashley Drobot,2 Mubashir Aslam Arain3 1Stollery Awasisak Indigenous Health, Alberta Health Services, Edmonton, Alberta, Canada; 2Health Systems Evaluation and Evidence, Alberta Health Services ...
Di Lallo S   +4 more
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Evaluation of Prototype Discharge Planning Model Based on Information Technology

open access: yesMakara Journal of Health Research, 2010
Discharge Planning (DP) is very important to be conducted as is provides patient and his/her family with homecare preparation. This study aimed at identifying the implementation of DP model and evaluated the DP model. Sampel of the research was 51 nurses
Rr. Tutik Sri Hariyati   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Analysis of structured discharge planning implementation for discharged inpatients: a multicenter study

open access: yesHealthcare in Low-resource Settings
Discharge planning is an approach taken by the nurse, patient, and family that includes a needs assessment that will address a detailed care plan after the patient is discharged from the hospital.
Candra Dewi Rahayu   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Planeamento de alta hospitalar: perspetivas e reflexões acerca dos protelamentos sociais em Portugal

open access: yesAlternativas, 2018
Introdução: O objetivo deste artigo é compreender e analisar o fenómeno dos protelamentos sociais em Portugal e em particular do Centro Hospitalar Lisboa Central.
Ines Espirito Santo   +1 more
doaj   +1 more source

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